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3beta-hydroxy-5alpha-androstan-17-one On Body Composition And Muscular Strength

This article talks about a special substance called 3beta-hydroxy-5alpha-androstan-17-one and its effects on our bodies, especially muscles. Scientists found this chemical back in 1931, and it seems to play a big role in how much muscle we can grow and how much fat we carry.

For folks who lift weights, taking this could make them stronger and leaner — one study showed people getting more muscular with less fat after using it for four weeks. But there's a catch; it might not be safe for everyone.

It can mess with your heart health, liver, or even lead to hair loss among other things. Plus, you're not allowed to use it in sports because it gives an unfair advantage.

There's more to learn about how this substance works and whether the perks are worth the risks. Stick around!

Key Takeaways

  • 3beta-hydroxy-5alpha-androstan-17-one, or epiandrosterone, helps people build muscle and lose fat by changing into stronger substances like testosterone in the body.
  • Taking this supplement can increase muscle mass by 6.3% and reduce body fat by about 24.6%, making workouts more effective.
  • Using epiandrosterone comes with risks such as heart disease, liver problems, and mood changes. It's important to talk to a doctor first.


Understanding 3beta-hydroxy-5alpha-androstan-17-one

3beta-hydroxy-5alpha-androstan-17-one, or epiandrosterone as many know it, is a substance that the body makes from a hormone called dehydroepiandrosterone (DHEA). Think of it like a building block in the world of hormones.

Discovered back in 1931 by scientists Adolf Friedrich Johann Butenandt and Kurt Tscherning, this compound has fascinated researchers for its unique properties. With its chemical formula C19H30O2 and a molar mass of 290.447 g·mol−1, it stands out in the crowd of synthetic androgens.


Epiandrosterone plays a crucial role in the natural pathway of steroid hormones.


It helps our bodies use fat and build muscle by turning into stronger substances like testosterone when needed. This process happens without us even knowing, influencing everything from how we gain muscle to how quickly we can run or lift weights.

Unlike anabolic steroids that people might take to get bigger muscles faster, epiandrosterone comes from within us – making it quite special indeed.

Role of 3beta-hydroxy-5alpha-androstan-17-one in Body Composition

This substance plays a big part in shaping our bodies. It affects how much muscle we have and where fat goes on our body.

Effect on Muscle Mass

This substance helps people gain more muscle. In a study with 17 men who did strength training, those who took this substance saw their muscles grow by 6.3%. This means it can make muscles bigger and stronger than just working out alone.

Taking this product changes how your body looks and feels. Muscles get bigger faster, making training more effective. It's like giving your workout an extra boost, leading to more muscle in less time.

This is great for anyone wanting to look stronger and be healthier without waiting too long.

People use this to get better results from their exercises. It's not magic, but it helps a lot when you're trying to improve your body's shape and power through lifting weights or other strength activities.

Impact on Fat Distribution

This compound changes where fat sits in the body. Studies, like the one with people having 13.1% body fat at first, show it works well. They lost about 24.6% of their unwanted fat after taking this supplement.

This means less belly and more muscle.

Users see big changes in how they look because of this shift in fat storage. The drop in fat levels helps muscles show more and improves health too. People end up looking leaner and feeling stronger without extra weight slowing them down.

The Connection between 3beta-hydroxy-5alpha-androstan-17-one and Muscular Strength

This chemical can help muscles get stronger. It makes workouts better, helping people lift more and run longer.

Enhancement of Resistance Training Gains

Taking 330 mg/day of 3beta-hydroxy-5alpha-androstan-17-one for four weeks has shown a big step up in how well people do with their resistance training. This boost means they saw a 14.3% rise in what they could lift during back squats and their total competition scores.

This shows that adding this supplement to a workout plan can make muscles stronger and more powerful.

The improvement is not just about being able to lift heavier weights or perform better in competitions. It also affects how quickly muscles recover after exercise, letting athletes train harder and more often without as much risk of injury or fatigue.

Plus, the increase in muscle mass from using this supplement helps burn more fat, making it easier to maintain a lean body composition.

Such gains come from how the substance works with the body's natural systems, improving protein synthesis in the muscles - key for growth and repair. This process makes each training session more effective, leading users to see results faster than by lifting weights alone.

With careful use and attention to dosage, those looking to enhance their resistance training outcomes might find this addition beneficial for reaching their fitness goals quicker.

Influence on Muscle Power and Endurance

After focusing on how this substance aids resistance training, we now shift to its effects on muscle power and endurance. This shift is crucial for athletes wanting more from their workouts.

Stronger muscles do not just mean lifting heavier weights. They also mean running faster, jumping higher, and lasting longer in any physical activity.

Studies show significant improvements in the muscular strength of those using the prohormone group as part of their routine. It's not just about being stronger; it's about sustaining that strength over time and through various activities.

This is where endurance kicks in – the ability to keep going when others might have to stop.


Endurance isn't just the ability to bear a hard thing, but to turn it into glory.


Muscle power isn't just for show; it directly impacts how well someone can perform in sports or even daily tasks requiring strength and stamina. With improved endurance, users find they're not as quick to tire out.

They can push through tougher workouts or longer runs without feeling spent too soon.

The Impact of 3beta-hydroxy-5alpha-androstan-17-one on User Health

This stuff can change how healthy you are. It might cause problems with your liver or change blood fat levels.

Potential Side Effects

Taking supplements like 3beta-hydroxy-5alpha-androstan-17-one can change your body. But, it's important to know it can also cause some side effects. Here’s a list of possible issues you could face:


  1. Infertility issues - This supplement might mess with your body's natural hormone balance. It could make it hard for you to have kids in the future.
  2. Changes in how you act - You might feel more angry or sad than usual. Your mood could change fast, which isn't fun for you or those around you.
  3. Losing hair - No one likes to lose their hair, but taking this supplement might speed up that process.
  4. Liver troubles - Your liver works hard to clean your blood and help digest food. This supplement could harm it, leading to serious health issues.
  5. Heart risks - Using this product might increase your chances of getting heart disease, which is scary because your heart is key to keeping you alive and well.
  6. Creatinine levels go up - Creatinine is a waste product in your blood that comes from muscle use. High levels can mean your kidneys aren’t working right.
  7. Liver enzymes change - Specifically, aspartate transaminase levels might rise, signaling liver damage or stress.


Each point shows how important it is to think carefully and maybe talk to a doctor before using supplements like 3beta-hydroxy-5alpha-androstan-17-one.

Precautions and Warnings

Epiandrosterone, a substance that some people use to try to boost muscle strength and change their body shape, comes with rules. Just like any powerful tool, it needs careful handling. Here's what you need to know before you think about using it.


  1. Legal status matters: Epiandrosterone is on the list of Schedule III controlled substances in the US. This means having it without a prescription is not legal.
  2. Sports bans: Planning to compete? The World Anti-Doping Agency (WADA) says no to epiandrosterone. Getting caught using it can end your sports career.
  3. Health risks are real: Using this substance might harm your liver function and mess with your kidney’s work too. Keeping an eye on how your body parts like these are doing is key.
  4. Side effects aren't fun: From small issues like skin problems to big worries like harming your heart, epiandrosterone comes with risks. You could also see changes in mood that you didn't expect.
  5. Mixing it up can be bad: Taking epiandrosterone with other supplements or meds can cause trouble. It’s smart to talk with a doctor first about everything you're taking.
  6. Dosage is delicate: More isn’t always better. Sticking to recommended amounts helps lower the chance of bad effects.
  7. Listen to your body: Signs like unusual tiredness or yellow skin mean stop and seek medical help right away.
  8. Not for everyone: If you have certain health issues already, using epiandrosterone might not be safe at all.


For those thinking about adding epiandrosterone to their routine, going slow and getting advice from healthcare pros make a big difference in staying safe while chasing fitness goals.

Interactions of 3beta-hydroxy-5alpha-androstan-17-one with Other Substances

Mixing 3beta-hydroxy-5alpha-androstan-17-one with other substances can change how it works. Some things make it work better, while others might cause problems. For example, if you take vitamins or herbal supplements, the way your body handles 3beta-hydroxy-5alpha-androstan-17-one could shift.

This is because everything you put into your body interacts in some way.

Certain drugs can also affect how well 3beta-hydroxy-5alpha-androstan-17-one does its job. Medications for liver or kidney issues need special attention. Since this product is made from DHEA by an enzyme called 5α-reductase, anything that affects these organs might alter its impact.

It's a bit like mixing different ingredients in a recipe – not all combinations turn out well.

Checking with a healthcare provider makes sense before starting new pills or supplements alongside 3beta-hydroxy-5alpha-androstan-17-one. They can help steer clear of bad mixes and ensure everything taken together is safe and effective.

Also, understanding the possible side effects helps manage them if they happen. This careful approach ensures that benefits are maximized without unexpected surprises along the way.

The Use and Effectiveness of 3beta-hydroxy-5alpha-androstan-17-one Supplements

Taking 3beta-hydroxy-5alpha-androstan-17-one supplements could change how your muscles grow and how fat spreads in your body. Read on to see what they can do for you!

Dosage Recommendations

Figuring out the right amount of 3beta-hydroxy-5alpha-androstan-17-one to take can be tricky. The aim is to get the benefits without any harm.

Here's a simple guide to follow:


  1. Start with a low dose: Experts suggest starting with a smaller amount than you think you need. This helps your body adjust without shock.
  2. Follow study guidelines: In recent research, individuals took 330 mg per day for four weeks. This is seen as a safe and effective level.
  3. Listen to your body: If you feel any discomfort or see signs your body isn't happy, it might be time to lower the dose.
  4. Talk to a professional: Before adding anything new to your routine, getting advice from someone who knows their stuff is wise.
  5. Keep an eye on the calendar: Taking this supplement for longer than recommended in studies could lead to unknown effects.
  6. Measure changes in your body: Keeping track of how your muscle and fat levels change can help you figure out if the supplement works for you.
  7. Consider breaks: Sometimes, taking short breaks from supplements helps ensure they remain effective when you use them again.
  8. Be mindful of other things you take: Mixing different supplements or medications can affect how 3beta-hydroxy-5alpha-androstan-17-one works for you.


Expected Results

After figuring out the right dosage, let's talk about what you might see. Taking this supplement could make your muscles bigger and stronger. It does so by changing how your body builds muscle and burns fat.

You might notice more muscle mass and less fat on your body.

This mix can also help people lift more weight and keep going longer when they work out. So, if someone is training hard, they might find that they can do a bit more each time. Also, these benefits come with some risks to health.

Users should watch for any bad effects on their health.

Studies and Research on 3beta-hydroxy-5alpha-androstan-17-one

Research on this substance shows it might change your muscle strength and body shape. Experts have looked into how it works. They use tests, checks on body health, and look at changes in muscles to understand its effects better.

This work helps us know if taking this supplement is safe and effective for getting stronger and changing fat into muscle. If you're curious about how this could help you or any risks it might have, looking more into these studies could give you answers.

Evidence of Benefits

Studies show taking 3beta-hydroxy-5alpha-androstan-17-one can lead to good changes in the body. People saw a 6.3% rise in lean body mass and a 24.6% drop in fat body mass. This means they got more muscle and lost fat.

Also, their strength improved a lot. They could lift heavier weights, with a 14.3% increase in back squat one-repetition maximum and competition total.

This proves that this supplement can help make muscles stronger and reduce fat. Many people who work out or train might find these results exciting because it means better performance and healthier bodies without unwanted fat.This is all backed by research and numbers, showing how effective it can be for those looking to boost their fitness journey.

Concerns and Criticisms

Some people worry about taking 3beta-hydroxy-5alpha-androstan-17-one because it can make HDL (good) cholesterol levels go down and LDL (bad) cholesterol levels go up. This change might hurt the heart and liver.

Studies show that using this substance could lead to heart disease or liver problems like cholestasis, which stops the normal flow of bile in the liver. These risks are real for people who use it a lot over a long time.

Doctors also caution against mixing this with other drugs without professional advice. It might interact badly with things like blood lipid regulators or medications for diabetes, making health problems worse.

People should always check with their doctors before starting any new supplement, especially one that affects hormones and metabolism so strongly.


Always consult your healthcare provider before beginning any new supplement regimen to ensure it aligns with your individual health needs.


Next, let's look at how individuals use these supplements safely to avoid potential risks.


This substance really changes muscle and fat in the body. People get stronger and leaner when they use it. But, it can be tough on the heart and liver. So, taking care with this stuff matters a lot.

It makes muscles bigger and helps with workouts but check with a doc first.


1. What is 3beta-hydroxy-5alpha-androstan-17-one?

It's a type of natural product, you know, like something your body might make or you find in supplements. People look at it for building muscles and changing how much fat they have.

2. Can this stuff change how strong my muscles are?

Yes, it can! This thing works kind of like those performance enhancers – think about athletes wanting to be stronger. It helps with muscular strength but always check because not everything is good for everyone.

3. Does taking it mess with my health?

Well, there's talk about that... Things like liver and kidney stuff could happen. Also, your heart needs to stay healthy, right? So if someone uses too much or the wrong way, it might not be so good.

4. Will it make me gain weight in a bad way?

Not exactly "bad" weight... It’s more about muscle than fat accumulation when used right. But remember – balance is key! Too much of anything isn't great.

5. How does this all work inside my body?

So here's the deal - when you take it, your body starts doing different things with hormones and fats (like HDL cholesterol which is a good guy) and even sugar levels get involved which affects insulin sensitivity.

6. Is there anything else I should watch out for while considering this supplement?

Think about what you're aiming for and chat with a doc first maybe? Because things like blood tests (to check on liver function or serum creatinine) are important to keep an eye on... Plus, knowing all the effects – from muscle gains to possible changes in how your body handles fats and sugars – helps make smarter choices.

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